Biology » The Immune System » Disruptions in the Immune System

Summarizing Disruptions in the Immune System


Immune disruptions may involve insufficient immune responses or inappropriate immune targets. Immunodeficiency increases an individual’s susceptibility to infections and cancers. Hypersensitivities are misdirected responses either to harmless foreign particles, as in the case of allergies, or to host factors, as in the case of autoimmunity. Reactions to self components may be the result of molecular mimicry.



immune reaction that results from immediate hypersensitivities in which an antibody-mediated immune response occurs within minutes of exposure to a harmless antigen


antibody that incorrectly marks “self” components as foreign and stimulates the immune response


type of hypersensitivity to self antigens


spectrum of maladaptive immune responses toward harmless foreign particles or self antigens; occurs after tissue sensitization and includes immediate-type (allergy), delayed-type, and autoimmunity


failure, insufficiency, or delay at any level of the immune system, which may be acquired or inherited

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