From the words lettered A to E below the following sentence, choose the word or ...

This question is asking you to choose the word that means the same thing as "exacerbate" in the sentence "There are some drugs that could exacerbate a particular illness." The options are heal, ameliorate, lengthen, worsen and detect. "Exacerbate" means to make something worse. So, you need to choose the word that means "make worse" from the options given.

Option A, "heal", means to make something better, so it is not the correct answer. Option B, "ameliorate", means to improve something, so it is also not the correct answer. Option C, "lengthen", means to make something longer, so it is not the correct answer. Option D, "worsen", means to make something worse, which is the same meaning as "exacerbate" in the sentence, so it is the correct answer. Option E, "detect", means to discover or notice something, so it is not the correct answer.

In summary, the word "exacerbate" means to make something worse. Therefore, the correct answer from the options given is option D, "worsen".