Summarizing Cancer and Gene Regulation Summary Cancer can be described as a disease of altered gene expression. Changes at every level of eukaryotic gene expression can be detected in some form of cancer at some point in time. In order to understand how changes to gene expression can cause cancer, it is critical to understand how each stage of gene regulation works in normal cells. By understanding the mechanisms of control in normal, non-diseased cells, it will be easier for scientists to understand what goes wrong in disease states including complex ones like cancer.
Glossary DNA methylation epigenetic modification that leads to gene silencing; commonly found in cancer cells
histone acetylation epigenetic modification that leads to gene silencing; commonly found in cancer cells
myc oncogene that causes cancer in many cancer cells
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